Monday, December 28, 2015

PHARMACEUTICAL CHEMISTRY – I,University Of Pune Question Paper,2010 Question Paper,First Year B.Pharmacy

University Of Pune Question Paper
First Year B.Pharmacy Examination, 2010
Time : 3 Hours Max. Marks : 80
 Instructions : 1) Question No. 1 from Section I and Question No. 5 from
Section II are compulsory.
2) Out of remaining questions solve 2 questions from Section
I and 2 questions from Section II.
3) Answers to the two Sections should be written in separate
4) Figure to the right indicate full marks.
1. a) Discuss the role of major extracellular and intracellular electrolytes. 8
b) Write principle involved in limit test for lead. 2
2. a) Explain role of fluoride and phosphate in tooth decay. 5
b) Define hardness of water and state the methods to remove hardness of
water. 5
c) What is radiopaque contrast media ? Explain barium sulphate as radiopaque
contrast media. 5
3. a) Explain the role of Iron in body. 5
b) Enlist sources of impurities in pharmaceutical substances and explain their
effect on pharmaceutical substances. 5
c) Describe limit test for Iron. 5
4. a) Define antidote, discuss different antidotes with their mechanism of
action. 5
b) Define monograph. Elaborate contents of monograph. 5
c) Discuss in brief applications of radiopharmaceuticals. 5
5. a) What are protective and adsorbents ? Describe two official compounds used
as protective. 5
b) Define the terms buffer, emetics, cathartics, antacid and expectorant. 5
6. a) Classify topical agents on the basis of their actions with example. 5
b) Discuss in brief antioxidants. 5
c) Define and classify inorganic Gastrointestinal agents. 5
7. Write short notes on (any five) : 15
a) Astringents
b) Protectives
c) Assay of KI
d) Assay of NH4
e) Combination Antacids
f) Preservatives.
8. a) Discuss in brief antimicrobial agents. 5
b) Discuss the source, physiological importance and compounds of Iodine. 5
c) Explain the role of oxygen, carbon dioxide in human body. 5

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