Dr. A.P.J. Abdul Kalam University M.Pharm (Pharmacology) II Sem Advanced Pharmacology II [MPL201T] June 2021 Question Paper

Dr. A.P.J. Abdul Kalam University

Master of Pharmacy (Pharmacology)

Second Semester Examination, June-2021

Advanced Pharmacology II [MPL201T]

Time: 3:00 Hrs Max Marks 75

Note: Attempt any five questions. All questions carry equal marks.

Q.1 (a) What is free radical brief note on free radical mechanism and role of free

radical in etiopathology of various disease.

 (b) Write the mode of action of contraceptives pills and their ADR.

Q.2 (a) Write brief notes on cellular mechanism and classification of growth

hormone drugs.

(b) Write the molecular mechanism action of insulin hormones and Their

pharmacotherapy.

Q.3 (a) Describe rational use of anti microbial agents with at least two examples.

(b) Write the molecular and cellular mechanism action of drug resistance.

Q.4 (a) Describe the classification, MOA, ADR and drug resistance of anti fungal

drugs.

 (b) Describe the classification, MOA, ADR and drug resistance of anti

viral drugs

Q.5 (a)What is the hypersensitive reaction describe the type of hypersensitivity

reaction with uses of drugs.

 (b) What is chrono-pharmacology ,describe the chrono-pharmacology

disease like diabetes and asthma.

Q.6 (a) Describe the classification, MOA, ADR and drug resistance of anti-cancer

drug.

 (b) Describe Difference between pharmacotherapy of asthma and

COPD.

 Q.7 (a) Write the basic mechanisms of inflammation and their biochemical mediator

 (b) What are Immunosuppressant and Immunostimulants. Explain ?

 Q.8 Short notes (Any 3)

a) Drug used in irritable bowel syndrome

b) Anti-emetics drugs

c) Drug used in constipation

d) Recent advances in treatment of cancer drug

e) Antioxidant

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