Thursday, January 7, 2016

Paper V – BIOCHEMISTRY – I,FIRST M.B.B.S.,2013 Question Paper,Dr. MGR University Question Paper

Dr. MGR University Question Paper
FIRST M.B.B.S. DEGREE EXAMINATION
Paper V – BIOCHEMISTRY – I
Q. P. Code : 524055
Time : 180 Minutes Maximum: 50 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
 1. Classify enzymes. Describe in detail the various factors affecting enzyme action.
 Add a note on enzyme regulation
 2. Name the ketone bodies? How are they formed and utilised in the body.
 Add a note on the metabolic changes in diabetic ketoacidosis.
II. Write notes on: (10 x 2.5 = 25)
1. 2,3 BPG- Formation & its role.
2. Mechanism of synthesis of ATP in ETC
3. Explain ‘Methyl Folate trap’
4. Carnitine shuttle
5. What are dietary fibres and explain their importance in human nutrition with
 respect to the prevention of diseases
6. Write briefly about the significance of HMP shunt pathway
7. Sources, RDA & Biological role of Vitamin C
8. Describe the energetics of complete oxidation of 1 mole of glucose to CO2 & H2O
 under aerobic conditions
9. Bile salts – Synthesis & biological role.
 10. Write briefly about calcium homeostasis.
III. Short Answers on: (10 x 1 = 10)
1. What are zymogens. Give an example
2. Mention two inhibitors of ETC with their site of action
3. What is specific dynamic action and importance in calculating caloric
 requirements of an individual.
4. What are trace mineral. Give RDA of any 2 of them.
5. What is Steatorrhoea ?
6. What is Suicide inhibition? Give an example
7. Laboratory Criteria for diagnosis of Diabetes Mellitus.
8. Name the insulin dependent glucose transporters and their tissue distribution.
9. What is pulmonary surfactant and its clinical importance?
 10. What is the biochemical basis of development of cataract in Diabetes Mellitus.
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