Friday, January 8, 2016

Dr. MGR University Question Paper,Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY,2011 Question Paper,SECOND M.B.B.S.

Dr. MGR University Question Paper
SECOND M.B.B.S. DEGREE EXAMINATION
Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
 1. Define Necrosis. Name the different types of necrosis.
 Discuss in detail with examples the different types of necrosis.
 Differentiate between Necrosis and Apoptosis.
 2. A 70 year old women admitted with worsening anemia and pathological fracture of
 the Humerus had an ESR of 120mm in 1 hour. Her peripheral smear showed
 increased rouleaux formation. Xray of skull showed multiple punched out osteolytic
 lesions.
 a. What is the most probable diagnosis? Write briefly on the etiopathogenesis of this
 disease.
 b. Describe the Bone Marrow Changes in this disease.
 c. Enumerate the common laboratory investigations for this disease.
 d. Enlist the complications of this disease.
II. Write Short notes on : (10 x 5 = 50)
 1. Role of Arachidonic Metabolites in inflammation.
 2. Pathogenesis of Septic Shock.
 3. Tumour Metastasis.
 4. Mitochondrial Inheritance.
 5. Etiopathogenesis of Cystic Fibrosis.
 6. Anemia of Chronic Disease.
 7. FAB classification of Acute Leukemia.
 8. Idiopathic Thrombocytopenic purpura.
 9. Transfusion Reaction.
 10. Hematocrit.
III. Short Answer Questions : (10 x 2 = 20)
1. Give four examples for pathological calcification.
2. Give four examples for Metaplasia.
3. Mention two differences between exudates and transudate.
4. Mention two renal changes in SLE.
5. Give two examples for trace elements and their deficiency states.
6. Give four causes for iron deficiency anaemia.
7. Mention two important marrow changes in B12 deficiency.
8. Two characteristic difference between Myeloblasts and Lymphoblasts.
9. Mention two pathognomonic features of Hairy cell leukemia.
 10. Mention four applications of reticulocyte count.
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