Tuesday, December 29, 2015

Fourth Year B.Pharmacy,2010 Question Paper,University Of Pune Question Paper,PHARMACEUTICS – IV

University Of Pune Question Paper
Fourth Year B.Pharmacy Examination, 2010
PHARMACEUTICS – IV
(2004 Course)
Time : 3 Hours Max. Marks : 80
Instructions : 1) Question No. 1 and 5 are compulsory. Out of the remaining
attempt 2 questions from Section I and 2 questions from
Section II.
2) Answers to the two Sections should be written in separate
books.
3) Neat diagrams must be drawn wherever necessary.
4) Black figures to the right indicate full marks.
SECTION – I
1. Explain types and formulation of LVPs. Give quality control tests of it. 10
2. Explain the concept and importance of optimization techniques in pharmaceuticals.
Explain factorial design method of optimization with suitable pharmaceutical
examples. 15
3. What packaging materials are used for parenterals ? Explain any one in detail
along with its evaluation tests. 15
4. Write short notes on (any three) : 15
a) Freeze dried parenteral products
b) HVAC systems for parenteral plants
c) Indicators used for evaluation of sterilization cycles
d) Equipment validation
e) Particulate matter contamination in parenterals.
SECTION – II
5. Explain importance of valve assembly and propellants in aerosol system. Give
quality control tests of aerosols. 10
6. Enlist methods for preparation of microencapsules. Explain mechanical
encapsulation process in detail. Give evaluation test for microencapsules. 15
7. Explain the concept of pharmacokinetic principles in the design of controlled
drug delivery systems. Explain drug release pattern from these systems. Discuss
parenteral controlled drug delivery systems. 15
8. Write short notes on (any three) : 15
a) Dried human plasma
b) Sonophoretic drug delivery system
c) Ocusert
d) Intrauterine devices
e) Liposome.


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