Wednesday, January 25, 2023

Dr. A.P.J. Abdul Kalam University M PHARMACY I SEM (ALL BRANCH) Modern Pharmaceutics (MPH 103T) Dec 2020 Question Paper

Dr. A.P.J. Abdul Kalam University

Master of Pharmacy (Pharmaceutics)

First Semester Main Examination, Dec-2020

Modern Pharmaceutics (MPH 103T)

Time: 3:00 Hrs Max Marks 75

Note : Attempt any five questions. All questions carry equal marks.

Q.1 (a) Explain in detail the physicochemical and biological factors affecting

stability of drug.

(b) Describe in brief ICH guidelines for stability studies.

Q.2 (a) Differentiate consolidation and compression with definition. Write a

detailed note on distribution and measurement of forces and physics of


(b) Define validation. Write its importance and its type.

Q.3 (a) Explain the various approaches for injectable controlled release


(b) Explain the role of the PH and tonicity adjustment in parenteral explain

with suitable examples

Q.4 (a) Describe production area design of high – purity water unit in pharma –


(b) Give detail of preparation and application of high purity water for

parenteral dosage form.

Q.5 (a) Write in detail about production management and GMP consideration for

the pharmaceutical industry.

(b) Explain in brief about safety measures in pharmaceutical industry.

Q.6 (a) Explain the experimental design approach used in the optimization of


(b) Write a short note on statistical design.

Q.7 (a) Explain in detail factorial design approach.

(b) Describe the use of ‘t’ test and standard deviation in evaluation of data.

Q.8 (a) Write a short note on application of linear regression of standard curve in

drug analysis.

(b) Give comparision between one way and two way ANOVA

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