Monday, December 28, 2015

University Of Pune Question Paper,2.2 : PHARMACEUTICCAL MICROBIOLOGY AND IMMUNOLOGY,Second,2010 Question Paper

University Of Pune Question Paper
Second Year B.Pharmacy Examination, 2010
 (2008 Course)
Time : 3 Hours Max. Marks : 80
Instructions: 1) Question Nos. 1 and 5 are compuslroy. OUt of the remaining
attempt 2 questions from Section I and 2 questions from
Section II.
2) Answers to the two Sections should be written in separate
3) Neat diagrams must be drawn wherever necessary.
4) Black figures to the right inidcate full marks.
1. Answer the following (any five) : 10
a) Write name and function of oil used for oil-immersion objective.
b) Write note on ‘Protozoa’.
c) Differentiate between Slime layer and Capsule.
d) GIve the general properties of viruses,.
e) Explain inshort ‘Bacterial reproduction’.
f) Write the contributions of Louis Pasteur for microbiology.
2. a) Describe in detail various methods used for measurement of bacterial growth. 8
b) Explain in detail principal and working of compound microscope. 7
3. Answer the following : 15
a) What are dermatophytes ? Explain it.
b) COmment on ‘Actinomycetes as source of antibiotics’.
c) Explain the different factors affecting the microbial spoilage of pharmaceutical
4. Write short notes (any three) : 15
a) Colony characteristics.
b) HIV.
c) Rickettsia.
d) Preservative efficacy test.
5. Answer the following : 10
a) Define :
i) Immunogen b) Z-value
b) Give the disadvantges of phenol coefficient test.
c) What is the selection criteria for test micro-organisms used for microbial
assay of vitamin ?
d) Write the biological effects of lymphokines released by T cells.
e) Give the Harmful role of normal microbial flora of the human body.
f) What are allergenic extracts ? Explain it.
6. a) Explain in detail nonspecific defence mechanism of human host against
pathogens. 8
b) WHat are different methods of sterillization ? Descirb in detail sterillization by
filtration. 7
7. Answer the following : 15
a) Explain in brief quality control of vaccine.
b) Describe in detail Type-I hypersensitivity.
c) Explain the principal and procedure of ELIISA.
8. Write a note on (any three) : 15
a) Designing of aspetic area.
b) MIC.
c) Immunoglobulins.
d) Factors affecting on disinfectant action.

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