Tuesday, December 29, 2015

2.4 : PHARMACEUTICAL ORGANIC CHEMISTRY – II,University Of Pune Question Paper,2010 Question Paper,Second Year B.Pharmacy

University Of Pune Question Paper
Second Year B.Pharmacy Examination, 2010
(2008 Course)
Time : 3 Hours Max. Marks : 80
Instructions :1) All questions are compulsory.
2) Answers to the two Sections should be written in separate
3) Neat diagram must be drawn wherever necessary.
4) Black figures to the right indicate full marks.
1. Give reaction, mechanism and application of any two rearrangement of electron
deficient carbon atom. 10
1. Explain any two nucleophilic rearrangement of electron deficient Nitrogen atom. 10
2. Answer the following (any five) : 15
a) What is Mutarotation ? Give its significance.
b) What are configurational and conformational isomers ? Write in brief about
c) How will you distinguish between glucose and fructose and glucose and
sucrose ?
d) What are amino acids ? Discuss any three methods of synthesis of amino
e) Draw the Newmann projection formulae of n-butane and discuss the energy
profile diagram of conformations in n-butane.
f) Discuss the constitution of Lactose.
g) Synthesize phenylalanine by Strecker’s synthesis.
3. Answer the following (any three) : 15
a) What are carbohydrates ? Draw the structure of glucose. What will happen
when glucose treated with i) Nitri acid ; ii) Bromine water ;
iii) Sodium borohydrate ?
b) What are proteins ? Discuss in brief about structure of protein.
c) What is racemic modification ? Enlist the different methods for resolution of
racemic mixture.
Discuss in brief about Diastereomer formation method in brief :
d) Write a short note on combinatorial chemistry.
e) Discuss stereoselective and stereospecific reaction with suitable examples.
4. a) Discuss Fischer-indole and Skraup quinoline synthesis method. 6
b) Write in brief about electrophilic substitution reactions of five membered
monoheterocyclic ring system. 4
4. Give the methods of synthesis and reactions of the following : 10
i) Thiazole
ii) Isoquinoline
5.Answer the following (any five) : 15
a) Give the structure and numbering of
i) Quinoline ii) Benzimidazole iii) Oxazole
b) Explain why pyridine is less reactive than benzene.
c) Discuss chair, boat and twist boat conformation of cyclohexane molecule.
d) Why pyridine undergose electrophilic substitution at β-position ?
e) Give the reaction and mechanism of Knorr-pyrrole synthesis.
f) Classify rearrangement reactions.
g) What is reterosynthesis ? Give the reterosynthesis of Losrtan.
6. Write short note on (any three) : 15
a) Fries rearrangement
b) Curties rearrangement
c) Hoffman rearrangement
d) Willgerodt reaction
e) Lossen rearrangement.

Share This
Previous Post
Next Post

B.E Civil Engineer Graduated from Government College of Engineering Tirunelveli in the year 2016. She has developed this website for the welfare of students community not only for students under Anna University Chennai, but for all universities located in India. That's why her website is named as www.IndianUniversityQuestionPapers.com . If you don't find any study materials that you are looking for, you may intimate her through contact page of this website to know her so that it will be useful for providing them as early as possible. You can also share your own study materials and it can be published in this website after verification and reviewing. Thank you!


Pen down your valuable important comments below

Search Everything Here