Sunday, November 22, 2015

2.2 : PHARMACEUTICAL MICROBIOLOGY AND IMMUNOLOGY,2013 Question Paper,University Of Pune Question Paper,Second Year B. Pharmacy

University Of Pune Question Paper
Second Year B. Pharmacy Examination, 2013
2.2 : PHARMACEUTICAL MICROBIOLOGY AND IMMUNOLOGY
 (2008 Pattern)
Time : 3 Hours Max. Marks : 80
Instructions : 1) Answers to the two Sections should be written in
separate books.
2) Neat diagrams must be drawn wherever necessary.
3) Black figures to the right indicate full marks.
4) All questions are compulsory.
SECTION – I
1. Why we study detail structure of bacteria ? Draw and label typical structure of
bacteria and give the function of each part. 10
OR
Give the classification of viruses. Describe lytic and lysogenic cycle of
bacteriophage. 10
2. Answer the following (any five) : 15
a) Classify bacteria based on their requirement for temperature and oxygen.
b) List different preservatives used in pharmaceutical formulations.
c) How will you preserve microbial culture ? Explain it.
d) Write note on ‘spotted fever group’ of rickettsia.
e) Give the importance of actinomycetes.
f) What are dermatophytes ? Explain it.
g) Comment on ‘Agar is commonly used for the preparation of solid media’.
3. Write a note on (any three) : 15
a) Measurement of bacterial growth.
b) Historical development of microbiology.
c) Cultivation of human viruses
d) Fluoresence microscopy.
e) Sources and types of microbial contamination of pharmaceutical products.
P.T.O.
Seat
No.
[4355] – 202 -2-
SECTION – II
4. Define antigen and antibody. Explain in detail different antigen-antibody reactions
and give their significance. 10
OR
Define disinfectant. Describe different classes, action and uses of disinfectants. 10
5. Answer the following (any five) : 15
a) Differentiate between immediate and delayed hypersensitivity.
b) What are adjuvants ? Give their significance.
c) Enlist the test microorganism used for antibiotic assay.
d) What is 100 class clean area ? Give particulate matter test as per I.P.
e) Write the applications of monoclonal antibody.
f) Draw and describe basic structure of immunoglobulin.
g) Write note on “Gaseous sterilization’.
6. Write note on (any three) : 15
a) Immunity
b) BCG
c) Sterilization monitors
d) Comparison of hypersensitivity reactions
e) MIC
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