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## Dr. MGR University Question Papers

### 2010 Question Paper

B.S.M.S. DEGREE EXAMINATION.
First Professional Course
(Pattern – VI Candidates admitted from 2007-2008 onwards)
Paper III – UYIR VEDHIYAL
(BIOCHEMISTRY)
Q.P. Code : 601120
Time : Three hours Maximum : 100 marks
SECTION - A
I. Answer in Detail: (2 x 15 = 30)
1. Discuss the formation, transport, biochemical functions and metabolic fate of thyroid
hormones.
2. Describe Denova synthesis of Fatty Acids.
SECTION - B
II. Write Short notes on: (10 x 5 = 50)
1. Glycoside.
2. Glucose Tolerance Test (GTT).
3. Functions of Phospholipid.
4. Genetic Code.
5. Anti Retro Viral Therapy (ART).
6. Paper chromatography.
7. Replication.
8. Respiratory Quotient of Food Stuff.
9. Niacin.
10. Phenyl ketonuria.
SECTION - C
III. Write Short Answers: (10 x 2 = 20)
1. What is enolization?
2. What are antioxidants? Write the name of the three vitamins which has antioxidant property?
3. What is Isolectric pH?
4. Define Michaelis-Menten constant.
5. Name the catecholamines.
6. Names and symptoms of protein-energy malnutrition diseases.
7. Detoxification by Conjugation.
8. What are oncogenes?
9. What is Diabetes Insipidus?
10. How does the “Human Immuno deficiency virus”(HIV) get entry into the cells and cause
lysis?
___________

## Dr. MGR University Question Paper

### 2010 Question Paper

B.S.M.S. DEGREE EXAMINATION.
(FIRST PROFESSIONAL COURSE)
Paper III —UYIR VEDHIYAL (BIOCHEMISTRY)
Q.P. Code : 601120
Time : Three hours Maximum : 100 marks
I. Answer in detail : (2 × 15 = 30)
1. Describe the Tricarboxylic Acid cycle with its energetics and add a note on the
conversion of Pyruvate to Acetyl. CoA.
2. Give an account of Beta-Oxidation of Fatty Acids and Ketogenesis.
II. Write short notes on : (10 × 5 = 50)
1. The components and reactions of Electron Transport Chain.
2. Digestion and absorption of Carbohydrates.
3. Reactions in the synthesis of Urea.
4. Principle, Technique and application of Polymerase Chain Reaction.
5. Degradation of heme to Bile Pigments.
6. The Watson and Crick model of DNA structure.
7. Biochemical functions of Pyridoxine.
8. Structure and metabolic effects of Insulin.
9. Biochemical functions of calcium and factors regulating plasma calcium level.
10. List out the names of Renal, Thyroid and Liver function Tests.
2 [KY 1120]
III. Write short answer : (10 × 2 = 20)
1. Repeating unit and types of Mucopolysaccharides.
2. Define Essential Fatty Acids with examples.
3. Zwitter ion and Peptide bond.
4. Active site.
5. Gout.
6. Applications of Bioinformatics.
7. Biochemical actions of Prostaglandins.
8. Multiple Mycloma.
9. Specific Dynamic Action.
10. Laboratory Diagnosis of AIDS.
———————

## Dr. MGR University Question Paper

### 2011 Question Paper

B.S.M.S. DEGREE EXAMINATION.
First Professional Course
Paper III - UYIR VEDHIYAL
(BIOCHEMISTRY)
Q.P. Code : 601120
Time : Three hours Maximum : 100 marks
I. Long Essay : (2 x 15 = 30)
1. Describe the process of glycolysis, formation of acetyl CoA from pyruvate
and citric acid cycle.
2. Write an essay on the dietary sources, daily requirement, absorption, transport,
storage, biochemical functions, deficiency symptoms and disorders of iron.

II. Short notes : (10 x 5 = 50)
1. Degradation of cholesterol and its products.
2. The factors affecting enzyme activity.
3. High energy compounds in metabolism.
4. Digestion and absorption of lipids.
5. Catabolism of heme in the body.
6. Catabolism of purine nucleotides and the associated metabolic disorders.
7. Components and applications of Bio informatics.
8. Biochemical functions and deficiency symptoms of Pyridoxine.
9. Biosynthesis and biochemical functions of thyroid hormones.
10. Urea cycle.
III. Write Short answers : (10 x 2 = 20)
1. Name of phospholipids and glycolipids.
2. Clinical significance of alpha 1-antitrypsin.
3. What is ‘‘specific dynamic action’’?
4. Name of inborn errors of phenyl alanine and tyrosine.
5. Classification of lipoproteins and role of ‘‘Lecithin-Cholesterol acyl transferase’’
Enzyme.
6. Diagnostic importance of glycosylated hemoglobin.
7. Mechanism of detoxification.
8. What are Tumour Markers? Name of two important Tumour Markers.
9. List of tests to assess renal function.
10. What are the factors regulating water and electrolytes balance in our body?
————————

## Dr. MGR University Question Paper

### 2012 Question Paper

FIRST PROFESSIONAL B.S.M.S. DEGREE EXAM – AUGUST 2012.
Paper III — UYIR VEDHIYAL (BIOCHEMISTRY)
Q.P. Code : 601120
Time : 180 minutes Maximum : 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
1. Liver function test. (Max.) (Max.) (Max.)
2. Elaborate digestion and absorption of
carbohydrates.
16 25 min. 15
II. Write notes on :
1. Immunoglobulins. 3 8 min. 5
2. Parathyroid hormone. 3 8 min. 5
3. Explain Krebs – Henseleit cycle with diagram. 3 8 min. 5
4. Mechanism of oxidative phosphorylation. 3 8 min. 5
5. Discuss the biological functions and deficiency
manifestations of Vitamin D.
3 8 min. 5
6. Detail notes on Electrolyte balance. 3 8 min. 5
7. What do you know about cytochrome P450 ? 3 8 min. 5
8. Functions of copper. 3 8 min. 5
9. Biosynthesis of Heme. 3 8 min. 5
10. Detailed notes on Glycogen storage disease. 3 8 min. 5
III. Short answers : 1 5 min. 2
1. Tautomerization.
2. Emulsification. 1 5 min. 2
3. Achlorhydria. 1 5 min. 2
4. Isozymes. 1 5 min. 2
5. Pellagra. 1 5 min. 2
6. Glucosidases. 1 5 min. 2
7. Ketosis. 1 5 min. 2
8. Menke’s disease. 1 5 min. 2
9. Eicosonaids. 1 5 min. 2
10. Introns. 1 5 min. 2
———————

## Dr. MGR University Question Paper

### 2013 Question Paper

FIRST PROFESSIONAL B.S.M.S. DEGREE EXAMINATION –
Paper III — UYIR VEDHIYAL (BIOCHEMISTRY)
Q.P. Code : 601120
Time : Three hours Maximum : 100 marks
I. Essay : (2 × 15 = 30)
1. Embden Meyerhof pathway – Draw, explain and also write the production of
ATP.
2. Biosynthesis of protein – Draw and explain.
II. Short notes : (10 × 5 = 50)
1. Structure of tRNA.
3. Digestion and absorption of carbohydrate.
4. Complement system.
5. Draw and explain three phases of HIV interaction with the infected body.
6. Bio-chemical functions and abnormalities of thyroid hormones.
7. Metabolism of phosphorus.
8. Catabolism of heme.
9. Hemoglobinopathies.
10. Structure of immunoglobulins.
III. Short answers : (10 × 2 = 20)
1. Heparin.
2. Functions of lipids.
3. Give two examples for aminoacids with aliphatic side chain.
4. What are the bonds present in quaternary structure of protein?
5. What are the effect of substrate concentration on enzyme action?
6. Vitamin-A – functions.
7. Name the lipoproteins.
8. What are the functions of Iron?
9. Write any two functions of Liver.
10. Define Electrolyte balance.
———————

## Dr. MGR University Question Paper

### 2013 Question Paper

FIRST PROFESSIONAL B.S.M.S. DEGREE EXAMINATION – AUGUST 2013
Bio Chemistry
Paper III — UYIR VEDHIYAL
Q.P. Code : 601120
Time : Three hours Maximum : 100 marks
I. Essay Questions : (2 × 15 = 30)
1. The sequence of reactions and energy production in Glycolysis.
2. Biochemical functions and abnormalities of Calcium.
II. Short notes : (10 × 5 = 50)
1. Digestion and absorption of Proteins.
2. Biochemical functions of female sex hormones.
3. Reactions in the synthesis of urea.
4. Replication of Deoxy Ribonucleic Acid (DNA) in Prokaryotes.
5. Degradation of Hemoglobin to Bile pigments.
6. Names and functions of Prostaglandins.
7. Different types of Immunoglobulins and their functions.
8. Components of Electron Transport Chain.
9. Functions and deficiency symptoms of Vitamin C.
10. Renal Function Tests.
III. Short answers : (10 × 2 = 20)
1. Classification of Carbohydrates.
2. Essential Fatty acids.
3. Name of the Sulphur containing amino acids.
4. Types of Enzyme inhibition.
5. Name of the three types of genes involved in the development of Cancer.
6. The end product of Purine Metabolism.
7. Name of the hormones that regulate water and electrolyte balance.
8. Complement system of our body.
9. Mechanism of Detoxification.
10. Specific Dynamic Action.
———————

## Dr. MGR University Question Paper

### 2014 Question Paper

FIRST PROFESSIONAL B.S.M.S. DEGREE EXAMINATION –
Paper III — UYIR VEDHIYAL (BIOCHEMISTRY)
(E°º ÷Áv°¯À)
Q.P. Code : 601120
Time : Three hours Maximum : 100 marks
I. Essay : (2 × 15 = 30)
1. Bio-synthesis of fatty acids.
2. Hexose monophosphate shunt pathway.
II. Short notes : (10 × 5 = 50)
1. Mucopolysaccharide.
2. Structure of proteins.
3. Structure of DNA.
4. Metabolism of Vitamin D.
5. Biosynthesis of Heme.
6. Explain oxidative and substrate level phosphorylation with examples.
7. Synthesis and degradation of Glycine.
8. Salvage pathway for Purines.
9. Metabolism of Selenium.
10. Hormones of Adrenal Medulla – Bio-chemical functions, abormalities.
III. Short answers : (10 × 2 = 20)
1. Define Clearance.
2. Water balance.
3. Define Basal metabolic rate.
4. Replication is known as semi conservative – Why?
5. What is proteome?
6. What are the two phases of Xenobiotics?
7. What is eicosanoids?
8. Functions of Insulin.
9. What are the causative agents of cancer?
10. Write two immunological abnormalities of AIDS.
———————

## Dr. MGR University Question Paper

### 2014 Question Paper

FIRST PROFESSIONAL B.S.M.S. DEGREE EXAMINATION
PAPER III – UYIR VEDHIYAL (BIO CHEMISTRY)
Q.P. Code : 601120
Time: Three hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
1. Describe protein biosynthesis in detail
2. Explain synthesis of cholesterol
II. Short Notes: (10 x 5 = 50)
1. Draw and explain structure of RNA
2. Factors affecting enzyme action
3. Transport of iron
4. Respiratory Quotient of Food stuffs
5. Vitamin A
6. Functions of Plasma Proteins
7. Essential amino acid
8. Properties of Triacyl glycerol
9. ά Thalassemia
10.Progesterone
III. Short notes: (10 x 2 = 20)
1. Multiple myeloma
3. Chromo protein
4. Oncogene
5. Bile acid
6. Co enzyme
7. Diagnostic test for AIDS
8. Transcription
9. Mutation
10.Glycoside
******

## Dr. MGR University Question Paper

### 2015 Question Paper

FIRST PROFESSIONAL B.S.M.S. DEGREE EXAMINATION
PAPER III – UYIR VEDHIYAL (BIO CHEMISTRY)
Q.P. Code : 601120
Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
1. Draw and explain the steps in Glycolysis and also energy production in
Glycolysis.
2. Discuss the formation, biochemical functions and metabolic fate of Thyroid
hormone.
II. Write Notes on: (10 x 5 = 50)
1. β oxidation.
2. Absorption of Lipids.
3. Discuss the biological functions of Vitamin D.
5. Draw and explain the structure of DNA.
6. Explain ATP – ADP cycle.
7. Write about biochemical functions of sodium.
8. Different types of Immunoglobulin and their function.
9. Specific dynamic action.
10.Essential fatty acid.
III. Short notes on: (10 x 2 = 20)
1. Name the sulphur containing amino acid.
2. Heparin.
3. Pellegra.
4. Name two important tumour marker.
5. Gout.
6. Protein energy malnutrition diseases.