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Saturday, January 30, 2016

BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS Dr. MGR University 2011 - 2015 Question Papers

Dr. MGR University MAY 2011 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[KY 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
(Regulations 2010)
(For candidates admitted from 2010-2011 onwards)
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions
I. Elaborate on : (6 x 10 = 60)
 1. What are steroids? Discuss the chemistry and stereochemistry of Cholesterol.
 2. Give the industrial method of isolation and estimation of
 a) Sennosides.
 b) Diosgenin.
 3. Elaborate on the screening methods of cardiac activity of natural products.
 4. Give a detailed note on anti fertility activity.
 5. Dwell on the industrial method of isolation and estimation of
 a) Tannic acid.
 b) Pectin.
 6. Explain the biosynthesis, isolation and estimation of Atropine.
II. Write notes on : (8 x 5 = 40)
 1. Psychopharmacological activity.
 2. Forskolin.
 3. Estimaton of Digoxin.
 4. Isolation and purification of Insulin.
 5. Chemical structure, estimation and uses of Quinine.
 6. Production of Vitamin B12.
 7. Antineoplastic activity.
 8. Hepatoprotective activity.
*******

Dr. MGR University OCTOBER 2011 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[KZ 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
(Max.) (Max.) (Max.)
 1. Discuss the biosynthesis, chemistry, isolation and
 estimation of Digoxin. 17 40 min. 20
 2. Describe in details the various methods used for
 screening of Hepato protective and Diuretic activity. 17 40 min. 20
II. Write notes on :
 1. Aromatic biosynthesis. 4 10 min. 6
 2. Preparation of corticosteroids. 4 10 min. 6
 3. Industrial methods of isolation of Quinine. 4 10 min. 6
 4. Industrial methods of isolation of Hesperidin. 4 10 min. 6
 5. Chemistry and estimation of Vitamin-A. 4 10 min. 6
 6. Isolation and estimation of Oxytocin. 4 10 min. 6
 7. Screening for Hypoglycemic activity. 4 10 min. 6
 8. Biosynthesis of Vinblastine. 4 10 min. 6
 9. Carbohydrate utilization. 4 10 min. 6
10. Biosynthesis and chemistry of Tetracyclines. 4 10 min. 6
*******

Dr. MGR University MAY 2012 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LA 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
(Max.) (Max.) (Max.)
 1. Describe in detail about various methods of screening of 17 40 min. 20
 natural products for
 (i) Antineoplastic activity
 (ii) Antifertility activity.
 2. Write in detail about the occurrence, chemistry, biosynthesis 17 40 min. 20
 and estimation of Penicillin.
II. Write notes on:
 1. Isolation and estimation of Atropine. 4 10 min. 6
 2. Screening of Invitro Antioxidant activity. 4 10 min. 6
 3. Isoprenoid Biosynthesis and its significance. 4 10 min. 6
 4. Chemistry of Insulin. 4 10 min. 6
 5. Chemistry of Vitamin-B12. 4 10 min. 6
 6. Screening for antiviral activity. 4 10 min. 6
 7. Chemistry and therapeutic uses of Tetracyclines. 4 10 min. 6
 8. Estimation and biosynthesis of Morphine. 4 10 min. 6
 9. Isolation and estimation of Tannic acid. 4 10 min. 6
10. Stereochemistry of Cholesterol. 4 10 min. 6
*******

Dr. MGR University OCTOBER 2012 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LB 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
(Max.) (Max.) (Max.)
 1. Occurrence, chemistry, biosynthesis, isolation and
 purification of Penicillin. 17 40 min. 20
 2. Screening methods of Cardiac activity and Antifertility
 activity of natural products. 17 40 min. 20
II. Write Notes on :
 1. Isolation and purification of Insulin. 4 10 min. 6
 2. Chemical structure, estimation and uses of Quinine. 4 10 min. 6
 3. Screening of Invitro antioxidant activity. 4 10 min. 6
 4. Biosynthesis and estimation of Atropine. 4 10 min. 6
 5. Industrial method of isolation and estimation of Pectin. 4 10 min. 6
 6. Hepatoprotective activity. 4 10 min. 6
 7. Production of Vitamin B12. 4 10 min. 6
 8. Isoprenoid biosynthesis. 4 10 min. 6
 9. Chemical structure & estimation of Sennosides. 4 10 min. 6
10. Isolation of Vasopressin and Oxytocin. 4 10 min. 6
*******

Dr. MGR University APRIL 2013 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LC 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions
I. Elaborate on : (2 x 20 = 40)
 1. Study of techniques employed in the elucidation of Biosynthetic pathways.
 2. General methods of screening natural products for
 a) Hypoglycemic activity and
 b) Diuretic activity.
II. Write notes on : (10 x 6 = 60)
 1. Aromatic Biosynthesis.
 2. Estimation of Digoxin.
 3. Chemical structure and uses of Atropine, Folic acid and Scillaren A.
 4. Industrial method of isolation and estimation of Citric acid.
 5. Antiulcer activity.
 6. Hepatoprotective activity.
 7. Steriochemistry of Cholesterol.
 8. Photosynthesis.
 9. Differentiate transpiration and guttation.
10. Isolation of Hesperidin.
*******

Dr. MGR University OCTOBER 2013 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LD 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions
I. Elaborate on : (2 x 20 = 40)
 1. Describe in detail about various methods of screening of natural products for
 a) Cardiac activity
 b) Hepato protective activity.
 2. Write in detail about the occurrence, chemistry, biosynthesis and estimation of
 ergometrine.
II. Write notes on : (10 x 6 = 60)
 1. Industrial methods of isolation and estimation of digoxin.
 2. Screening of diuretic activity.
 3. Biosynthesis of shikimic acid pathway and its significance.
 4. Chemistry of oxytocin.
 5. Chemistry of Vitamin C.
 6. Screening for hypoglycemic activity.
 7. Chemistry and therapeutic uses of semisynthetic penicillin.
 8. Estimation and biosynthesis of folic acid.
 9. Industrial methods of isolation and estimation of quinine.
10. Tracer techniques.
*******

Dr. MGR University APRIL 2014 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LE 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions
I. Elaborate on : (2 x 20 = 40)
 1. Write an account on the occurrence, chemistry, biosynthesis, isolation and estimation
 of vinblastine.
 2. Write a detail note on the biological evaluation of plant products for
 a) Psychopharmacological activity.
 b) Antiulcer activity
II. Write notes on : (10 x 6 = 60)
 1. Photosynthesis and its significance.
 2. Isoprenoid biosynthesis and its significance.
 3. Chemistry of scillaren-A.
 4. Industrial methods of isolation and estimation of sennosides.
 5. Screening for antibacterial activity.
 6. Chemistry and estimation of vasopressin.
 7. Screening for anti-inflammatory activity.
 8. Industrial methods of isolation and estimation of digoxin.
 9. Chemistry, estimation and therapeutic uses of tetracyclines.
10. Chemistry and estimation of vitamin A.
*******

Dr. MGR University OCTOBER 2014 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LF 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions
I. Elaborate on : (2 x 20 = 40)
 1. Describe the occurrence, biosynthesis, chemistry, isolation and estimation of morphine.
 2. Discuss the biological screening of natural products for
 a) Anti-inflammatory activity.
 b) Antiviral activity.
II. Write notes on : (10 x 6 = 60)
 1. Chemistry and biosynthesis of digoxin.
 2. Industrial methods of isolation and estimation of diosgenin.
 3. Chemistry and estimation of oxytocin.
 4. Chemistry and biosynthesis of atropine.
 5. Aromatic biosynthesis and its significance.
 6. Screening natural products for diuretic activity.
 7. Chemistry of corticosteroids.
 8. Industrial methods of isolation and estimation of forskolin.
 9. Tracer techniques and its applications.
10. Screening natural products for antiulcer activity.
*******

Dr. MGR University OCTOBER 2015 Question Paper
Subject : PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS

[LG 348] Sub. Code: 2909
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH III – PHARMACOGNOSY
PAPER III – BIOGENESIS AND CHEMISTRY OF NATURAL PRODUCTS
Q.P. Code : 262909
Time: Three Hours Maximum: 100 marks
Answer ALL questions
I. Elaborate on : (2 x 20 = 40)
 1. Discuss in detail about the Biosynthesis, Chemistry, Isolation, and Purification of
 Penicillin.
 2. Describe in detail about various methods of screening of natural products for Hepato
 Protective Activity.
II. Write notes on : (10 x 6 = 60)
 1. Photosynthesis.
 2. Methods of isolation and purification of Vasopressin.
 3. Chemistry of Reserpine.
 4. Vitamin - B12.
 5. Industrial method of isolation of Quinine.
 6. Screening of natural products for antiviral activity.
 7. Industrial methods of isolation and estimation of Diosgenin.
 8. Chemistry and estimation of Scillaren-A.
 9. Industrial method of isolation of Forskolin.
10. Industrial method of isolation of Pectin.
******* 

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