Sunday, July 12, 2015

WBUT B.Sc Microbiology B.Sc (H) MEDICAL MICROBIOLOGY (Sem-6) Question Paper 2013

University:West Bengal University of Technology
Course: B.sc
Subject :  MEDICAL MICROBIOLOGY
Year of  Question Paper : 2013

CS/B.Sc(H)/(MICRO-BIO)/SEM-6/MDM-602/2013

2013

MEDICAL MICROBIOLOGY

Time Allotted : 3 Hours Full Marks : 70

The figures in the margin indicate full marks.

Candidates are required to give their answers in their own words

as far as practicable.

GROUP – A

( Multiple Choice Type Questions )

1. Choose the correct alternatives for any ten of the following

questions : 10 × 1 = 10

i) Ability of pathogen to establish infection is called

a) Infectivity b) Prevalence

c) Toxigenicity d) Virulence.

ii) Typical bacterial pathogen that act extracellularly is

a) Vibrio cholerae b) Chlamydia

c) Salmonella sp d) S. aureus.

iii) Some intracellular parasites which are so highly evolved

that they cannot survive at all outside their host's cells

are

a) Rickettsia b) Pseudomonas sp

c) Salmonella sp d) S. aureus.

iv) .............. indicates the presence of the organism

without clinical or subclinical disease.

a) Colonization b) Infection

c) Pathogenesis d) Morbidity.

v) Negri bodies are produced in the

a) nerve cells b) liver cellsc) intestine d) blood.

vi) Pseudomonas aerugenosa causes

a) throat infection b) eye infection

c) peptic ulcer d) none of these.

vii) Norwalk agent is

a) bacteria b) protozoa

c) virus d) archea.

viii) Black Death is caused by

a) Rotovirus b) Salmonella typhi

c) Yersinia protis d) all of these.

ix) AZT is an analogue of

a) Adenine b) Guanine

c) Thymine d) Thymidine.

x) ............... is a bacterium that can only live in the

human bloodstream or intestinal tract.

a) S. aureus b) Salmonella typhi

c) Vibrio cholerae d) Chlamydia.

xi) Tetracycline is the usual antibiotic of choice for

a) Cholera b) TB

c) AIDS d) Amoebiasis.

xii) Neisseria gonorrhoea is inhibited by

a) Ofloxacin b) Tetracycline

c) Penicillin d) Lotrimin.

xiii) Toxin which act on the extracellular matrix of

connective tissue is

a) collagenase b) tetanolysin

c) choleragen d) M. protein.

xiv) Which is a Gram-negative, microaerophilic bacteriumthat can inhabit various areas of the
stomach and

duodenum ?

a) Bacillus b) Streptococcus

c) Helicobacter pylori d) S.mutans.

xv) Nosocomial infections is predominantly caused by

a) Bacillus b) Streptococcus

c) Pseudomonas d) S.mutans.

xvi) Toxic shock syndrome is caused by

a) Staphylococcus b) Streptococcus

c) Listeria d) Bacillus.

GROUP – B

( Short Answer Type Questions )

Answer any three of the following. 3 × 5 = 15

2. What do you mean by zoonosis ? Name two zoonotic

diseases. Write in brief the mode of transmission of plague

and its prevention. 1 + 1 + 3

3. Write about the normal microbiota of skin and respiratory

tract. 2.5+2.5

24. What is toxic shock syndrome ? Name the causative

organism for toxic shock syndrome. What are the symptoms

for toxic shock syndrome ? 1 + 1 + 3

5. What do you mean by MIC (Minimum Inhibitory Count) ?

Differentiate MIC from LD50. Describe how the MIC of an

antibacterial agent is determined. 1 + 2 + 2

6. Classify toxins produced by pathogenic bacteria. Write in

brief about endotoxins. 2 + 3

GROUP – C

( Long Answer Type Questions )Answer any three of the following. 3 × 15 = 45

7. Write short notes on any three of the following : 3 × 5

a) Cyclic polypeptide antibiotic

b) Isonicotinic hydrazide and Nalidixic acid

c) Actinomycetes used in chemotherapy

d) Colonization of growth of bacteria during infection.

8. a) Distinguish between pathogenicity and virulence.

b) Discuss the bacterial component needed for host

attachment during infection.

c) State the current epidemics of acute respiratory

syndrome.

d) Why does bacterial infection not occur on eyes ?

e) Name one virus that causes common cold.

3 + 6 + 3 + 2 + 1

9. a) Describe the structure and mode of action of cholera

toxin with proper diagram.

b) Also mention the mode of action of tetanus toxin.

c) Identify five mechanisms responsible for antibiotic

resistance. 5 + 5 + 5

10. a) What are the causative agents of malaria, plague, rabies

and typhoid ?

b) Write the mode of action of malaria along with the

symptoms.

c) Write the organisms and etiology of gastric ulcer.

4 + 6 + 5

11. a) Write causative agent, symptoms and preventive

measures of leprosy and tuberculosis.

b) Name the pathogen of diphtheria and whooping cough.c) Name three normal microbial floras in
the upper

respiratory tract. 10 + 2 + 3

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